|
Description |
Ki 67 Mouse Monoclonal Antibody(REK0128) |
|
Cat. No. |
REK0128 |
|
Immunogen |
synthetic peptide coupled to KLH. |
|
Concentration |
1ug/ul |
|
Specificity |
The Ki 67 mouse monoclonal antibody can detect endogenous Ki 67 proteins. |
|
MW |
N/A |
|
Substrate/Buffer |
Phosphate buffered saline (PBS) with containing 0.02% sodium azide. pH 7.2. |
|
Application |
WB 1:5000 (Optimal dilutions should be determined by the end user) |
|
Notes |
Antigen KI-67 is a nuclear protein that is associated with and may be necessary for cellular proliferation. Furthermore it is associated with ribosomal RNA transcription. Inactivation of antigen KI-67 leads to inhibition of ribosomal RNA synthesis. The Ki-67 protein (also known as MKI67) is a cellular marker for proliferation. It is strictly associated with cell proliferation. During interphase, the Ki-67 antigen can be exclusively detected within the cell nucleus, whereas in mitosis most of the protein is relocated to the surface of the chromosomes. Ki-67 protein is present during all active phases of the cell cycle (G1, S, G2, and mitosis), but is absent from resting cells (G0). |
|
Storage |
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. |
|
Purity |
Immunogen affinity purified |
|
Clonality |
Monoclonal |
|
Isotype |
IgG1 |
|
Alternative names |
Antigen identified by monoclonal antibody Ki 67 antibody, KIA antibody, Proliferation related Ki 67 antigen antibody |